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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: A modular framework for the development of targeted Covid-19 blood transcript profiling panels

Fig. 3

Delineation of sets of Covid-19 relevant A31 modules. a Transcript abundance profiles of A31 modules in Covid-19 patients. This heatmap represents the abundance levels for transcripts forming modules belonging to aggregate A31 (rows), across three Covid-19 patients (P1–P3) relative to one uninfected control subject (columns). The data are expressed as the proportion of constitutive transcripts in each module being significantly increased (red circles) or decreased (blue circles). b Transcript abundance profiles of A31 modules in reference disease cohorts. The top heatmap represents the abundance levels for transcripts forming modules belonging to aggregate A31 (rows), across 16 reference patient cohorts (columns). The bottom heatmaps represent the changes in abundance across the individuals comprised in two relevant patient cohorts, including pediatric patients with severe influenza or RSV infection and adult patients with sepsis

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