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Table 1 Screening clinical variables related to prognosis by univariate analysis in TNBC cohort

From: Comprehensive analysis and establishment of a prediction model of alternative splicing events reveal the prognostic predictor and immune microenvironment signatures in triple negative breast cancer

  OS PFS
  HR 95% CI P HR 95% CI P
Risk 24.311 3.264 181.084 0.002 20.068 4.771 84.404 0.000
Age 1.018 0.985 1.052 0.288 1.006 0.978 1.034 0.699
AJCC
 I-II     0.000     0.000
 III-IV 6.079 2.492 14.829 0.000 4.879 2.259 10.535 0.000
 NA 1.203 0.138 10.462 0.867 1.300 0.171 9.866 0.800
M
 0     0.323     0.001
 1 3.478 0.677 17.864 0.135 18.603 3.882 89.139 0.000
 NA 1.223 0.280 5.339 0.789 1.219 0.364 4.084 0.748
N 4.468 1.746 11.430 0.002 2.994 1.423 6.296 0.004
T
 1-2     0.190     0.131
 3-4 2.574 0.931 7.116 0.068 2.425 1.026 5.735 0.044
 NA 0.000 0.000 0.000 0.981 0.000 0.000 0.000 0.983
Radiotherapy
 No     0.000     0.001
 Yes 0.315 0.121 0.826 0.019 0.439 0.173 1.111 0.082
 NA 0.060 0.017 0.207 0.000 0.159 0.060 0.419 0.000
Race
 Asian     0.304     0.791
 White 0.192 0.023 1.571 0.124 0.363 0.046 2.834 0.334
 Black 0.361 0.044 2.973 0.344 0.435 0.054 3.521 0.435
 NA 0.000 0.000 0.000 0.985 0.000 0.000 0.000 0.980
  1. HR hazard ratio, AJCC American Joint Committee on Cancer, NA not applicable