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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Comprehensive analysis and establishment of a prediction model of alternative splicing events reveal the prognostic predictor and immune microenvironment signatures in triple negative breast cancer

Fig. 6

Selection of the optimal survival-related AS events in TNBC used for construction of the final prediction model by using Upset plot and LASSO Cox regression based on OS and PFS. a Upset plots of the intersections between the seven types of survival-related AS events. b LASSO coefficient profiles of the candidate survival-related AS events. A coefficient profile plot was produced against the logλ sequence. LASSO coefficient profiles of the candidate survival-related AS events. c Dotted vertical lines were drawn at the optimal values by using the minimum criteria. The upper parts and the bottom are related to OS and PFS, respectively. AS alternative splicing, TNBC triple negative breast cancer, LASSO least absolute shrinkage and selection operator, OS overall survival, PFS progression-free survival

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