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Table 1 Baseline characteristic of participants according to different BP patterns diagnosed by criterion A

From: Correction to: White-coat hypertension and incident end‑stage renal disease in patients with non‑dialysis chronic kidney disease: results from the C‑STRIDE Study

 

Total (N = 1714)

NT (N = 672)

WCH (N = 81)

MH (N +  (N = 529)

SH (N = 432)

P

Age (years)

48.9 ± 13.8

46.7 ± 14.4

53.1 ± 14.4a

49.9 ± 12.8ab

50.0 ± 13.3ab

< 0.001

Male, n (%)

974 (56.8%)

321 (47.8%)

38 (46.9%)

318 (60.1%)ab

297 (68.8%)abc

< 0.001

BMI (kg/m2)

24.6 ± 3.9

23.9 ± 3.6

25.0 ± 4.0a

24.8 ± 3.8a

25.6 ± 4.1ac

< 0.001

Smokers, n (%)

623 (36.8%)

188 (28.2%)

24 (30.8%)

213 (40.7%)a

198 (46.7%)abc

< 0.001

DM, n (%)

366 (24.7%)

94 (16.5%)

18 (26.1%)a

123 (26.9%)a

131 (34.2%)abc

< 0.001

CVD history, n (%)

155 (9.0%)

41 (6.1%)

12 (14.8%)

55 (10.4%)

47 (10.9%)

0.004

Anti-hypertension, n (%) treatment

1245 (76.7%)

380 (61.8%)

66 (85.7%)a

422 (81.8%)a

377 (90.8%)ac

< 0.001

Causes of CKD*

     

< 0.001

 DKD

212 (12.4%)

35 (5.2%)

11 (13.6%)a

73 (13.8%)a

93 (21.5%)abc

 

 GN

1048 (61.1%)

489 (72.8%)

40 (49.4%)a

313 (59.2%)a

206 (47.7%)ac

 

 Others

442 (25.8%)

144 (21.4%)

29 (35.8%)a

140 (26.5%)

129 (29.9%)a

 

 ALB (g/L)

38.3 ± 7.4

38.7 ± 7.2

39.4 ± 5.2

38.2 ± 7.6

37.7 ± 7.9a

0.1

 FBG (mmol/L)

4.9 (4.4, 5.6)

4.8 (4.3, 5.4)

5.0 (4.5, 5.5)

4.9 (4.4, 5.7)a

5.0 (4.5, 5.9)a

0.004

 HGB (g/L)

126.5 ± 22.4

127.7 ± 19.55

121.9 ± 22.2a

126.3 ± 24.2

125.7 ± 24.5

0.1

 TG (mmol/L)

1.8 (1.2, 2.5)

1.7 (1.2, 2.4)

1.8 (1.3, 2.4)

1.9 (1.3, 2.6)a

1.9 (1.3, 2.6)a

0.004

 TC (mmol/L)

4.7 (3.9, 5.7)

4.7 (3.9, 5.7)

4.6 (3.8, 5.5)

4.7 (3.9, 5.6)

4.7 (3.9, 5.7)

0.8

 HDLC (mmol/L)

1.1 (0.9, 1.3)

1.1 (0.9, 1.4)

1.0 (0.9, 1.3)

1.0 (0.9, 1.3)a

1.1 (0.9, 1.2)a

0.001

 LDLC (mmol/L)

2.6 (2.1, 3.2)

2.6 (2.1, 3.2)

2.6 (2.1, 3.2)

2.5 (2.1, 3.2)

2.7 (2.2, 3.3)

0.5

 Cr (μmol/L)

98 (141, 198)

116.0 (80.0, 164.2)

153.0 (106.7, 218.4)a

151.0 (108.0, 204.5)a

167.0 (122.0, 243.2)ac

< 0.001

 eGFR (mL/min/1.73 m2)

52.2 ± 30.1

62.9 ± 32.7

43.3 ± 24.3a

48.2 ± 28.2a

42.2 ± 23.3ac

< 0.001

 24 h-Upro (g/L)

1.0 (0.4, 2.4)

0.7 (0.3, 1.5)

1.0 (0.4, 2.9)a

1.1 (0.4, 2.5)a

1.8 (0.8, 3.5)abc

< 0.001

CKD stages, n (%)

     

< 0.001

 1

256 (14.9%)

174 (25.9%)

5 (6.2%)a

55 (10.4%)a

22 (5.1%)ac

 

 2

305 (17.8%)

144 (21.4%)

11 (13.6%)

90 (17.0%)

60 (13.9%)a

 

 3

676 (39.5%)

228 (33.9%)

36 (44.4%)

220 (41.6%)a

192 (44.5%)a

 

 4

477 (27.8%)

126 (18.8%)

29 (35.8%)a

164 (31.0%)a

158 (36.6%)a

 
  1. * The diagnosis was made mainly basing on medical history and clinical features, with only 578 patients having renal biopsy confirmation. Among them, 513 patients were diagnosed as GN. IgAN constituted the majority of GN group (54.2%), following by mesangial proliferative glomerulonephritis (32.2%) and membranous nephropathy (10.5%). Others group included hypertensive nephropathy, tubulointerstitial nephritis, and cause unknown etc
  2. aP < 0.05 comparison with NT
  3. bP < 0.05 comparison with WCH
  4. cP < 0.05 comparison with MH