From: Comprehensive molecular profiling of intrahepatic cholangiocarcinoma in the Chinese population and therapeutic experience
Gene
Number (%)
Amplification
 ERBB2
10 (8)
 CDK12/FAM135B/FRS2/MDM2
5 (4)
 CCNE1/KRAS
4 (3)
Deletion
 ADAM29/CDKN2A
6 (5)
 NTRK1/NTRK3
2 (2)
 NRG3/TP53/MLH1/SMARCA2
1 (1)
Rearrangement
 BCL2L11
9 (7)
 PBRM1
 ALK/FGFR3(-TACC3)