Fig. 2
Expression of immune response genes do not provide a survival difference in NSCLC. a Heatmap of immune response genes for AD and SCC ordered according to the average expression of the genes. Top bar indicates the histology as assessed by pathology: green represents AD, yellow SCC. b Waterfall plot of average expression of immune response related genes, both for AD (left panel) and SCC (right panel). Samples above the average are ‘hot’ tumors (red), the samples below ‘cold’ (blue). c Box plot for expression of the immune response related genes per histology. ***p < 0.001. d Box plot for expression of CD8A per histology. ***p < 0.001. e Box plot for mean tumor cell percentages per histology. ***p < 0.001. f Bar graph of each tumor cell percentage group for both AD (green) and SCC (yellow) samples. g Kaplan–Meier plots with the probability of survival of ‘hot’ versus ‘cold’ tumors in stage I/II tumors, both for AD and SCC