Table 1 Angiogenic cargo of tumor cell-derived exosomes
From: Tumor cells derived-exosomes as angiogenenic agents: possible therapeutic implications
Source cells | Angiognic cargo |
|---|---|
Breast cancer | Annexin II, Heparanase, TGFβ, miR-126a |
Bladder cancer | EDIL-3 |
Colorectal cancer | Plexin B2, Tetraspanin-8 |
Glioblastoma | Angiogenin, CXCR4, FGFa, IL-6, IL-8, MMP2, MMP9, TGFβ, TIMP-1, TIMP-2, VEGF |
Lung cancer | Sortilin, miRNA-21, miRNA-23a, miRNA-210 |
Glioma | IGFBP1, IGFBP3, IGFBP5, IL-8, LOXL2, VEGF |
Ovarian cancer | miRNA-21 |
Leukemia | Heparanase |
Nasopharyngeal cancer | CD44v5, HAX-1, ICAM-1, MMP13 |
Malignant melanoma | VEGF, MMP2, IL-6 |
Multiple myeloma | Angiogenin, Heparanase, HGF, MMP9, Serpin E1, Serpin F1, VEGF |