From: The timeline and risk factors of clinical progression of COVID-19 in Shenzhen, China
Characteristics | Total (N = 323) | Progressive (N = 70) | Stable (N = 253) | P value |
---|---|---|---|---|
Median age (years) | 46.0 (33.0–59.0) | 59.5 (49.0–64.0) | 41.0 (32.0–56.0) | < 0.001 |
Age groups (years): | < 0.001 | |||
≤ 18 | 35 (10.8%) | 0 (0%) | 35 (13.9%) | |
19–40 | 106 (32.8%) | 9 (12.9%) | 97 (38.3%) | |
41–65 | 150 (32.5%) | 46 (65.7%) | 104 (41.1%) | |
> 65 | 32 (9.9%) | 15 (21.4%) | 17 (6.7%) | |
Sex: | 0.002 | |||
Male | 154 (47.7%) | 45 (64.3%) | 109 (43.1%) | |
Female | 169 (52.3%) | 25 (35.7%) | 144 (56.9%) | |
Comorbidities | 72 (22.3%) | 30 (42.9%) | 42 (16.6%) | < 0.001 |
Incubation period | 7 (4,12) | 7 (3–12) | 7 (4.0–11.5) | 0.994 |
From Onset to admission(days) | 3 (1–5) | 4 (2–6) | 3 (1–5) | 0.006 |
Hospital stay (days) | 18 (14–22) | 21 (18.5–23) | 17.5 (14.0–21.0) | 0.003 |
Exposure history: | ||||
Living in Shenzhen with outside contact | 167 (51.7%) | 24 (34.3%) | 143 (56.5%) | < 0.001 |
From outside to Shenzhen | 127 (39.3%) | 33 (47.1%) | 94 (37.2%) | 0.130 |
No obvious exposure | 11 (3.4%) | 5 (7.1%) | 6 (2.4%) | 0.051 |
Related to Wuhan | 173 (53.6%) | 40 (57.1%) | 133 (52.6%) | 0.490 |
Signs and symptoms | ||||
Respiratory rate > 24 breaths per min | 5 (1.5%) | 3 (4.3%) | 2 (0.8%) | 0.036 |
Heart rate >100 per m in | 62 (19.2%) | 17 (24.3%) | 45 (17.8) | 0.222 |
Systolic pressure (mm Hg) | 125.0 (115.0–136.0) | 132.0 (123.5–140.5) | 122 (112.0–133.0) | < 0.001 |
Temperature on admission | 37.0 (36.6–37.5) | 37.6 (36.9–38.0) | 36.8 (36.6–37.3) | < 0.001 |
Fever | 248 (76.8%) | 61 (87.1%) | 187 (73.9%) | 0.154 |
Cough | 160 (49.5%) | 48 (68.6%) | 112 (44.3%) | < 0.001 |
Expectoration | 74 (22.9% | 30 (42.9%) | 44 (17.4%) | < 0.001 |
Chest tightness | 16 (5.0%) | 9 (12.9%) | 7 (2.8%) | < 0.001 |
Dyspnea | 9 (2.8%) | 5 (7.1%) | 4 (1.6%) | 0.012 |
Myalgia or fatigue | 69 (21.4%) | 26 (37.1%) | 43 (17.0% | < 0.001 |
Diarrhea | 24 (7.4%) | 7 (10.0%) | 17 (6.7%) | 0.354 |
Headache | 26 (8.0%) | 10 (14.3%) | 16 (6.3%) | 0.030 |
Anorexia | 40 (12.4%) | 15 (21.4%) | 25 (9.9%) | 0.009 |
Asymptomatic but nucleic acid positive | 24 (7.4%) | 2 (2.9%) | 22 (8.7%) | 0.100 |
Radiology manifestation | < 0.001 | |||
Unilateral involved | 35 (10.8%) | 3 (4.3%) | 32 (12.6%) | |
Bilateral involved | 255 (79.0%) | 67 (95.7%) | 188 (74.3%) | |
Normal | 33 (10.2%) | 0 | 33 (13.1%) |