Fig. 2

MiR-181a-5p level is a central nervous system involvement indicator in pediatric acute lymphoblastic leukemia. a Each dot indicates the miR-181a-5p expression of a patient. Horizontal line in box plots represents median fold change (FC), extent of boxes indicates upper and lower quartiles, whiskers show maximum and minimum values. b Lines are dedicated to follow the FC alterations in patient groups with and without meningeal leukemia and in a highlighted patient with progressive disease course during induction chemotherapy. Points indicate average FC values, while whiskers mark standard errors. CSF cerebrospinal fluid, CNS central nervous system, SMA spinal muscular atrophy, ΔFC difference in fold change