Fig. 4
Similar Histological Features Shared by All PDX Tissues and the Original Patient PDAC Tumors. The original poorly differentiated PDAC tumors from patients were histologically compared with their derived Patient 1275 PDX Tissue (a) or Patient 1319 PDX Tissue (b). Both PDX tissues were respectively passaged and expanded subcutaneously three times in the same mouse through incomplete resection, then engrafted and expanded orthotopically one time in the pancreatic tail of another mouse. Pictures were taken at magnifications indicated using an Olympusâ„¢ BX51 microscope