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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Mesenchymal stem cells activate Notch signaling to induce regulatory dendritic cells in LPS-induced acute lung injury

Fig. 5

MSCs induce the differentiation of mDCs into DCregs via the Notch signaling pathway. a, b The percentages of MHCII+, CD86+ and CD40+ based on CD11c+DC gate in mDC, Jagged1 and Jagged1+ DAPT groups. c, d The percentages of MHCII+, CD86+ and CD40+ based on CD11c+DC gate in DC + DMSO, DC + DAPT, MSC + DC + DMSO and MSC + DC + DAPT groups. n = 3, b *p < 0.05 versus mDC, #p < 0.05 versus Jagged1; d *p < 0.05 versus MSC + DC + DMSO; the data are expressed as the mean ± SD

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