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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Mesenchymal stem cells activate Notch signaling to induce regulatory dendritic cells in LPS-induced acute lung injury

Fig. 2

Tail vein injection of MSCs inhibited the recruitment and maturation of lung cDCs in ALI mice and improved pulmonary damage. a, b The percentage of lung cDCs in normal, ALI and MSC groups. c, d The percentage of MHCII+ or CD86+ cells in lung cDCs of mice in normal, ALI and MSC groups. eg The percentages of lung CD4+ T cells and CD69+ cells in CD4+ T cells in the normal, ALI, and MSC groups. h Lung wet weight to body weight ratio (LWW/BW) of mice in normal group, ALI group and MSC group. i, j Histopathological features of lung (hematoxylin and eosin staining; magnification, ×200) and lung injury score in the normal, ALI, and MSC groups. k, l The percentage of CFSE-labeled DCs in peripheral blood in normal group, ALI group and MSC group. m, n The percentage of CFSE-labeled DCs in the lung of mice in normal group, ALI group and MSC group. The data are presented as the mean ± SD. *p < 0.05 vs. the control group, #p < 0.05 vs. ALI group; n = 6 per group

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