Fig. 2

Volcano plot of gene expression changes in PBMC of MI patients compared to CTRLs. Blue dot indicates downregulated gene (log₂FC < −0.5); red dot indicates upregulated gene (log₂FC > 0.5), which passed threshold for multiple comparisons (p.adj < 0.05); Among differentially expressed genes (DEGs) MIR21 and its target genes are marked in orange, MIR223 and its target gene − in purple (−0.5 < log₂FC > 0.5, p < 0.05)