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Table 2 Proportion of patients within the therapeutic window

From: Clinical application of the AUC-guided dosage adjustment of docetaxel-based chemotherapy for patients with solid tumours: a single centre, prospective and randomised control study

 

Experimental (PK) group

Control (BSA) group

P value

Cycle 1

36.70 (0.87)

36.00 (0.81)

0.9166

Cycle 2

50.46 (0.62)

41.00 (0.66)

0.1705

Cycle 3

61.90 (0.50)

50.00 (0.58)

0.0928

Cycle 4

62.64 (0.42)

48.24 (0.58)

0.0546

Cycle 5

71.08 (0.43)

36.62 (0.72)

< 0.0001

Cycle 6

63.89 (0.43)

28.33 (0.59)

< 0.0001

  1. Data presented as  % (SD) unless otherwise indicated; SD standard derivation of AUC
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Journal of Translational Medicine

ISSN: 1479-5876

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