Respiration (pmol/s/mg) | Liver | Kidney | EDL | Soleus | ||||
---|---|---|---|---|---|---|---|---|
Control | TH | Control | TH | Control | TH | Control | TH | |
Endogenous | 9.0 ± 0.9 | 8.2 ± 0.9 | 21.3 ± 7.1 | 11.7 ± 7.0 | 4.8 ± 3.4 | 2.2 ± 0.8 | 2.2 ± 0.9 | 2.0 ± 0.4 |
Substrate | 13.5 ± 1.5 | 12.7 ± 1.6 | 39.7 ± 12.5 | 19.0 ± 2.2 | 26.2 ± 14.8 | 15.4 ± 6.7 | 23.5 ± 5.6 | 35.9 ± 16.1 |
ADP | 31.8 ± 5.3 | 22.1 ± 5.1 | 70.9 ± 23.0 | 30.8 ± 2.8* | 75.3 ± 40.7 | 42.5 ± 17.5 | 74.3 ± 22.6 | 121.3 ± 21.3# |
Succinate | 64.5 ± 6.9 | 42.6 ± 5.0* | 109.7 ± 39.0 | 61.0 ± 7.9 | 98.3 ± 37.7 | 50.6 ± 14.8 | 104.2 ± 22.3 | 152.0 ± 58.6# |
Olygomycin | 29.6 ± 2.0 | 24.5 ± 2.9 | 64.4 ± 16.3 | 43.1 ± 3.3* | 33.8 ± 8.6 | 16.1 ± 1.9* | 36.0 ± 3.6 | 41.8 ± 8.4# |
FCCP | 75.5 ± 9.0 | 44.3 ± 6.5* | 95.1 ± 26.1 | 57.8 ± 2.2 | 76.3 ± 13.6 | 39.6 ± 9.9* | 85.7 ± 20.5 | 117.0 ± 53.7# |
Ratenone | 39.3 ± 5.3 | 21.8 ± 2.5* | 52.7 ± 13.8 | 31.8 ± 3.7 | 34.1 ± 8.3 | 15.6 ± 1.3* | 36.6 ± 5.5 | 47.4 ± 19.0# |
Antimycin A | 6.5 ± 1.7 | 6.2 ± 1.2 | 13.1 ± 1.5 | 9.2 ± 1.0* | 5.1 ± 2.8 | 3.9 ± 1.9 | 6.9 ± 3.1 | 5.1 ± 1.5 |