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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Accumulation of blood-circulating PD-L1-expressing M-MDSCs and monocytes/macrophages in pretreatment ovarian cancer patients is associated with soluble PD-L1

Fig. 3

Expression profile of programmed death-ligand 1 (PD-L1). Simultaneusly analysis of PD-L1 on HLA-DR−/lowCD14+ monocytic myeloid-derived suppressor cells (M-MDSCs) and HLA-DR+CD14+ monocytes/macrophages (MO/MA) in the a, b blood, c ascites and d tumour tissue of patients with ovarian cancer. Mononuclear cells (MCs) obtained from the blood (n = 43), ascites fluid (n = 26), and tumour tissue (n = 29) of ovarian cancer patients and blood of healthy women (n = 15) were analyzed by flow cytometry. The frequencies of PD-L1+ cells are presented as the percentage of the total respective subsets (HLA-DR−/lowCD14+ M-MDSCs and HLA-DR+CD14+ MO/MA). The horizontal lines are the median values and the whiskers indicate the minimum and maximum values. Each point corresponds to an individual patient. **p < 0.01; ****p < 0.0001

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