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Table 4 Estimated population parameters for tazobactam using a modeling approach

From: Influence of extracorporeal membrane oxygenation on the pharmacokinetics of ceftolozane/tazobactam: an ex vivo and in vivo study

ParameterModel meanRSE (%)
Fixed effects
 Cl (l/h)24.27.86
 βECMO/Cl− 0.30435.2
 V1 (l)8.7116.6
 Q (l/h)7.1926.4
 V2 (l)6.3714.1
BSV (%)
 Cl11.344.9
 V132.438.7
 Q31.944.5
 V215.144.5
 Residual variability (%)19.910.8
  1. BSV between-subject variability, expressed as the coefficient of variation of the associated non-log-transformed parameter, RSE relative standard error