Table 4 Estimated population parameters for tazobactam using a modeling approach
Parameter | Model mean | RSE (%) |
|---|---|---|
Fixed effects | ||
Cl (l/h) | 24.2 | 7.86 |
βECMO/Cl | − 0.304 | 35.2 |
V1 (l) | 8.71 | 16.6 |
Q (l/h) | 7.19 | 26.4 |
V2 (l) | 6.37 | 14.1 |
BSV (%) | ||
Cl | 11.3 | 44.9 |
V1 | 32.4 | 38.7 |
Q | 31.9 | 44.5 |
V2 | 15.1 | 44.5 |
Residual variability (%) | 19.9 | 10.8 |