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Table 3 Estimated population parameters for ceftolozane using a modeling approach

From: Influence of extracorporeal membrane oxygenation on the pharmacokinetics of ceftolozane/tazobactam: an ex vivo and in vivo study

ParameterModel meanRSE (%)
Fixed effects
 Cl (l/h)6.159.83
 V1 (l)3.4136.9
 βSEX/V10.99835.1
 Q (l/h)9.6636.1
 V2 (l)9.9215.2
BSV (%)
 Cl23.531.4
 V12.48119
 Q68.736.8
 V226.638.3
 Residual variability (%)13.98.77
  1. BSV between-subject variability, expressed as the coefficient of variation of the associated non-log-transformed parameter, RSE relative standard error