Fig. 6
From: Development and optimization of orthotopic liver metastasis xenograft mouse models in uveal melanoma
a Fluorescent intensity in the splenic injection with splenectomy was monitored every week. Data were the mean radiant efficiency ± SEMs of 5 mice in each mouse model. b Mice body weights were measured twice per week. Values shown represent the mean ± SEMs. c Survival curve based on the number of injected cells (5 mice in each mouse model). Survivals were compared using the log rank test. d NSG mouse was injected with TJU-UM004 cells (1.0x106 cells/mouse)into the spleen and sacrificed 9 weeks after injection. HE staining and immunohistochemistry of SOX10, S100, and HMB45 were performed (100x). Scale bar = 500 μm