Dilution, % | Tumor purity, % | MSI score | MSI status |
---|
100 | 32 | 0.87 | MSI-H |
50 | 16 | 0.46 | MSI-H |
33 | 10.6 | 0.26 | MSS |
20 | 6.4 | 0.20 | MSS |
100 | 67 | 1.26 | MSI-H |
50 | 33.5 | 0.67 | MSI-H |
33 | 22.3 | 0.42 | MSI-H |
20 | 13.4 | 0.28 | MSS |
- Two MSI-H samples with tumor contents of 32% and 67% were selected for gradient dilution experiments by diluting tumor DNAs with their matched normal DNAs. The mixtures were tested for MSI status by USCI-msi
- MSI-H microsatellite instability-high, MSS microsatellite stability