Fig. 2

The performance of USCI-msi classifier. a USCI-msi was evaluated in the validation cohort (N = 36). MSI-H and MSS cases were grouped by MSI-PCR. The MSI status recognized by USCI-msi was consistent with those by MSI-PCR at the cutoff of 0.4. The mean MSI score of MSI-H samples (0.78, range 0.47–0.97) was significantly higher than that of MSS samples (0.06, range 0.04–0.10) (p < 0.0001). b A comparison among USCI-msi, MSI-PCR and IHC in the combination of training and validation cohorts. All MSI status recognized by USCI-msi were consistent with those by MSI-PCR, though only 85.2% (46/54) with IHC