Fig. 2

Module identification. a Identification of co-expression modules from the topological overlap matrix of GSE65682 using WGCNA. b Heatmap shows the reproducibility of two module lists. Rows represent modules identified from GSE65682 while columns represent modules from GSE69528. Grid color corresponds to –log10 transferred hypergeometric test P-values of the overlap of two modules. c Venn diagram of the identified modules from the two datasets. d Overview of the sepsis modules, including up-regulated DEMs, down-regulated DEMs, and SAMs. DEM, differentially expressed modules; SAMs, survival associated modules