Fig. 4

Significantly open chromatin and enriched TF binding motifs using by ATAC-seq analysis in HepG2 cells. The cells were treated with 25 μM of EGCG for 24 h. a ATAC-seq analysis of open chromatin heat map. b ATAC-seq analysis of open chromatin shows the PCSK9 promoter c Significantly enriched TF binding motifs (HNF1α and FoxO3).ct: control group; E25: 25 μM of EGCG; E200: 200 μM of EGCG