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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Efficacy of direct current generated by multiple-electrode arrays on F3II mammary carcinoma: experiment and mathematical modeling

Fig. 4

Survival versus days after inoculation of F3II cells in mice BALB/c/Cenp, by experimental group and gender. a Females. b Males. CG1 (first control group, in which C-I was used but DC was not applied). CG2 (second control group, in which C-II was used but DC was not applied). TG1 (first group treated with 2 mA for 10 min and C-I). TG2 (second group treated with 6 mA for 20 min and C-II). TG3 (third group treated with 2 mA for 10 min and C-III). TG4 (fourth group treated with 2 mA for 10 min and C-II). TG5 (fifth group treated with 6 mA for 10 min and C-II). TG6 (sixth group treated with 10 mA for 10 min and C-II). C-I was formed by four collinear electrodes with alternating polarities inserted perpendicularly along the largest diameter of the tumor (electrodes 1 and 3 were positives whereas electrodes 2 and 4 negatives), as shown in Fig. 1a. C-II were formed by four electrode pairs inserted into the tumor to 45° (electrode pair 1–2), 135° (electrode pair 3–4), 225° (electrode pair 5–6) and 325° (electrode pair 7–8), as shown in Fig. 1b. For C-II, electrodes 1, 4, 5 and 8 were positives whereas electrodes 2, 3, 6 and 7 negatives. C-III were formed by four electrode pairs arranged into the tumor to 0° (electrode pair 1–2), 90° (electrode pair 3–4), 180° (electrode pair 5–6) and 270° (electrode pair 7–8), as shown in Fig. 1c. For C-III, electrodes 2, 3, 5 and 8 were positives whereas electrodes 1, 4, 6 and 7 negatives

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