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Table 2 Intraoperative and postoperative characteristics of all patients, the glutamate group and the control group (saline)

From: The impact of glutamate infusion on postoperative NT-proBNP in patients undergoing coronary artery bypass surgery: a randomized study

VariablesAll patients
(n = 399)
Glutamate
(n = 200)
Control
(n = 199)
p-value
Aortic crossclamp time (min)50 [40–64]53 [39–63]48 [40–65]0.95
CPB time (min)76 [63–97]77 [62–97]76 [64–97]0.94
Reperfusion time (min)21 [15–29]20 [16–30]21 [15–28]0.49
NT-proBNP POD1 (ng•L−1)2175 [1340–3770]2220 [1484–4040]2041 [1236–3429]0.18
NT-proBNP POD3 (ng•L−1)3690 [2239–6065]3640 [2335–6155]3781 [2081–6020]0.95
Delta NT-proBNP POD1-Pre (ng•L−1)1590 [1029–2725]1640 [1069–2801]1522 [910–2640]0.49
Delta NT-proBNP POD3-Pre (ng•L−1)3067 [1617–5038]2995 [1671–5009]3110 [1580–5297]0.94
CK-MB POD1 (µg•L−1)15 [10–23]14 [10–23]15 [11–23]0.43
TroponinT POD3 (ng•L−1)250 [140–510]260 [150–490]250 [140–550]0.87
Delta troponin T POD3-Pre (ng•L−1)190 [95–385]195 [90–390]180 [100–370]0.84
Inotropic support24% (95)28% (56)20% (39)0.06
ICU stay (h)21 [17–23]20 [17–23]21 [17–24]0.21
ICU stay > 72 h6% (23)6% (12)6% (11)1
Ventilation time (h)4 [3–6]4 [3–6]4 [3–6]0.77
Ventilation time > 48 h3% (11)3% (6)3% (5)1
PHF10% (40)10% (19)11% (21)0.74
Severe PHF3% (10)2% (3)4% (7)0.22
Postoperative stroke2% (7)2% (4)2% (3)1
AKI15% (61)17% (33)14% (28)0.58
Hospital mortality1% (5)1% (2)2% (3)0.69
  1. Data given as medians [interquartile range] or percentages (number)
  2. AKI acute kidney injury, CK-MB creatine kinase-MB isoenzyme, CPB cardiopulmonary bypass, ICU intensive care unit, POD postoperative day