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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: microRNA-1271 impedes the development of prostate cancer by downregulating PES1 and upregulating ERβ

Fig. 1

Analysis of microarray data from on-line databases. A-B, Expression heatmaps of the DEGs from the datasets GSE3868 (a) and GSE30994 (b), in which the X axis refers to sample number, and the Y axis refers to gene names; the left dendrogram represents gene expression cluster; each square represents the expression of a gene in each sample; the upper right squares refer to color scale. c Venn diagram showing the DEGs from the datasets GSE3868 (the left circle) and GSE30994 (the right circle); the intersection showing the overlapped DEGs in the two datasets. d Gene interaction network of 7 DEGs retrieved from the expression datasets and 10 known prostate cancer-related genes obtained from the DisGeNET database; each circle represents a gene and the lines between the circles denote the interaction between genes. e Expression of PES1 in the TCGA database, in which the X axis refers to sample type, and the Y axis represents gene expression; the left box plot denotes the expression of PES1 in normal samples and the right box plot shows the expression of PES1 in prostate cancer samples. ***p < 0.001, vs. normal samples

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