Table 4 Differences in rs12696304 and rs2736100 genotyping between controls and patients with ESRD
Patients (M + F) | Odds ratio (95% CI) | P value | Controls (M only) | Patients (M only) | Odds ratio (95% CI) | P value | Controls (F only) | Patients (F only) | Odds ratio (95% CI) | P value |
|---|---|---|---|---|---|---|---|---|---|---|
516 (100%) | 289 (100%) | 300 (100%) | 226 (100%) | 216 (100%) | ||||||
51 (9.9) | 1.0 (ref.) | 32 (11.1) | 31 (10.3) | 1.0 (ref.) | 24 (10.6) | 20 (9.3) | 1.0 (ref.) | |||
186 (36.0) | 0.916 (0.598–1.403) | 0.686 | 119 (41.2) | 108 (36.0) | 0.937 (0.536–1.637) | 0.819 | 104 (46.0) | 78 (36.1) | 0.900(0.464–1.745) | 0.755 |
279 (54.1) | 1.298 (0.855–1.970) | 0.219 | 138 (47.7) | 161 (53.7) | 1.204 (0.699–2.074) | 0.502 | 98 (43.4) | 118 (54.6) | 1.445 (0.753–2.771) | 0.266 |
237 (45.9) | 1.0 (ref.) | 151 (52.3) | 139 (46.3) | 1.0 (ref.) | 128 (56.6) | 98 (45.4) | 1.0 (ref.) | |||
279 (54.1) | 1.392 (1.089–1.778) | 0.010 | 138 (47.7) | 161 (53.7) | 1.267 (0.917–1.752) | 0.176 | 98 (43.4) | 118 (54.6) | 1.573 (1.080–2.289) | 0.023 |
288 (27.9) | 1.0 (ref.) | 183 (31.7) | 170 (28.3) | 1.0 (ref.) | 152 (33.6) | 118 (27.3) | 1.0 (ref.) | |||
744 (72.1) | 1.245 (1.031–1.503) | 0.022 | 395 (68.3) | 430 (71.7) | 1.172 (0.913–1.504) | 0.213 | 300 (66.4) | 314 (72.7) | 1.348 (1.011–1.798) | 0.042 |
520 (100%) | 289 (100%) | 297 (100%) | 226 (100%) | 223 (100%) | ||||||
156 (30.0) | 1.0 (ref.) | 93 (32.2) | 104 (35.0) | 1.0 (ref.) | 65 (28.8) | 52 (23.3) | 1.0 (ref.) | |||
248 (47.7) | 0.977 (0.737–1.295) | 0.873 | 136 (47.1) | 134 (45.1) | 0.881 (0.610–1.273) | 0.500 | 121 (53.5) | 114 (51.1) | 1.178 (0.754–1.839) | 0.472 |
116 (22.3) | 1.175 (0.830–1.662) | 0.363 | 60 (20.7) | 59 (19.9) | 0.879 (0.558–1.387) | 0.580 | 40 (17.7) | 57 (25.6) | 1.781 (1.033–3.070) | 0.037 |
560 (53.8) | 1.0 (ref.) | 322 (55.7) | 342 (57.6) | 1.0 (ref.) | 251 (55.5) | 218 (48.9) | 1.0 (ref.) | |||
480 (46.2) | 1.075 (0.904–1.278) | 0.415 | 256 (44.3) | 252 (42.4) | 0.927 (0.736–1.168) | 0.519 | 201 (44.5) | 228 (51.1) | 1.306 (1.005–1.698) | 0.046 |