Fig. 5
From: Kinin B1 receptor: a potential therapeutic target in sepsis-induced vascular hyperpermeability
The role of R1B blockade on biological markers of organ dysfunction. Determination of the serum concentration of organ dysfunction markers: liver (ALP, ASAT, ALAT), kidneys (creatinine, urea) and lactatemia, at H30 post-surgery in wild-type mice. n = 7 to 10 per group. WT sham: sham-operated C57BL/6J controls; WT CLP: CLP-induced septic C57BL/6J mice; WT CLP R-954: CLP-induced septic C57BL/6J mice receiving prophylactic B1R antagonist R-954. Kruskal–Wallis test followed by a Dunn’s correction. *p < 0.05; **p < 0.01; ***p < 0.001. Results expressed in median ± IQR