Table 1 Patient and tumor characteristics for the analyzed group
Clinical parameter | No of cases 66 (%) | Pre-treatment viral load median (u.q.–l.q) [copies/ml] | cfHPV16 DNA in the 12th week | p value | |
|---|---|---|---|---|---|
Positive No of cases (%) | Negative No of cases (%) | ||||
Tumor classification | |||||
T1 | 14 (21) | 76 (25–177) | 0 (0) | 14 (23) | 0.327 |
T2 | 18 (27) | 1422 (191–7913) | 1 (17) | 17 (28) | |
T3 | 19 (29) | 2874 (203–12,320) | 2 (33) | 17 (28) | |
T4 | 15 (23) | 1548 (176–5239) | 3 (50) | 12 (20) | |
Nodal classification | |||||
p | 6 (9) | 61 (21–229) | 0 (0) | 6 (10) | 0.232 |
N0–N1 | 8 (12) | 1283 (252–3607) | 2 (330 | 6 (10) | |
N2–N3 | 52 (79) | 1489 (140–9092) | 4 (67) | 48 (80) | |
Treatment | |||||
RT | 6 (9) | 1722 (229–2022) | 0 (0) | 6 (10) | 0.405 |
CH-RT | 9 (14) | 7913 (167–13,412) | 2 (33) | 7 (12) | |
CH-CHRT | 30 (45) | 2071 (163–10,523) | 3 (50) | 27 (45) | |
CHRT | 21 (32) | 146 (36–1152) | 1 (17) | 20 (33) | |
Cigarette consumption | |||||
Never | 33 (50) | 545 (101–7913) | 3 (50) | 30 (50) | 0.734 |
≥ 5 years | 10 (15) | 1722 (163–23,008) | 0 (0) | 10 (17) | |
Current smokers | 23 (35) | 1396 (176–5600) | 3 (50) | 20 (33) | |