Cytokine network analysis of immune responses before and after autologous dendritic cell and tumor cell vaccine immunotherapies in a randomized trial

Table 9 Association between immunoglobulin levels and survival

	TCV < 60 (n = 17)		TCV 60+ (n = 5)		DCV < 60 (n = 12)		DCV 60+ (n = 5)
	Mean	Median	Mean	Median	Mean	Median	Mean	Median
Fold difference from normal values at baseline
IgG1	1.55	1.12	4.17	.98	1.62	1.41	3.75	1.73
IgG2	1.89	.49	2.33	1.09	2.49	.89	1.33	1.05
IgG3	3.55	3.25	2.72	2.53	4.99	4.09	2.58	3.01
IgG4	3.09	2.84	2.14	1.78	2.57	2.33	2.55	2.37
IgM	1.21	1.10	2.36	2.57	0.95	0.91	1.27	0.96
Fold difference compared to baseline after three injections
IgG1	− 1.32	− 0.48	− 1.00	− 0.05	0.22	0.03	− 0.74	− 0.31
IgG2	− 0.10	0.10	− 0.29	− 0.63	0.04	0.02	− 0.58	− 1.06
IgG3	0.04	0.05	− 0.28	0.18	− 0.12	− 0.08	− 0.12	0.09
IgG4	− 0.15	− 0.14	− 0.28	0.50	0.25	− 0.04	− 0.38	− 0.35
IgM	0.080	0.05	0.17	0.04	0.43	0.24	0.04	− 0.15

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