Table 2 The list of sixteen hub genes identified in gene expression network
Gene symbol | GeneModuleMembership | GeneTraitsignificance | Expression pattern |
|---|---|---|---|
PID1 | 0.915896493 | 0.66001985 | Down in stage I–II–up in stage II–III |
ABCA6 | 0.911773582 | 0.524366279 | Down in stage I–II–up in stage II–III |
TFPI | 0.903220611 | 0.599708264 | Down in stage I–II–up in stage II–III |
MPPED2 | 0.945621212 | 0.637198678 | Up in stage I–II–down in stage II–III |
RPS6KA6 | 0.932048783 | 0.611335416 | Up in stage I–II–down in stage II–III |
MRO | 0.931567859 | 0.632361438 | Up in stage I–II–down in stage II–III |
RMDN1 | 0.923154211 | 0.610969324 | Up in stage I–II–down in stage II–III |
ACACB | 0.919880602 | 0.610967988 | Up in stage I–II–down in stage II–III |
SLC4A4 | 0.913670371 | 0.575022712 | Up in stage I–II–down in stage II–III |
TTC30A | 0.912368213 | 0.563286233 | Up in stage I–II–down in stage II–III |
RNF150 | 0.909497328 | 0.625793803 | Up in stage I–II–down in stage II–III |
BCL2 | 0.909385573 | 0.588759014 | Up in stage I–II–down in stage II–III |
CASC2 | 0.908891219 | 0.567289908 | Up in stage I–II–down in stage II–III |
PRKCQ | 0.907179413 | 0.615140746 | Up in stage I–II–down in stage II–III |
SLC26A7 | 0.903842658 | 0.648569813 | Up in stage I–II–down in stage II–III |
ITPR1 | 0.900631876 | 0.587725656 | Up in stage I–II–down in stage II–III |