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Table 3 Genotype distribution and allele frequency of the tested SNPs in patients and controls

From: Serum sphingosine-1-phosphate levels and Sphingosine-1-Phosphate gene polymorphisms in acute respiratory distress syndrome: a multicenter prospective study

SNP Model Genotype Case Control OR (95% CI) P value
rs1049884 Additive T/T 2 1 1.173 (0.684–2.009) 0.5619
A/T 37 28
A/A 82 71
Codominant T/T 2 1 1.732 (0.1538–19.5) 0.6567
A/T 37 28 1.144 (0.6376–2.053) 0.6517
A/A 82 71
Dominant T/T,A/T 39 29 1.164 (0.6545–2.072) 0.6045
A/A 82 71
Recessive T/T 2 1 1.664 (0.1487–18.62) 0.6795
A/A,A/T 119 99
Allele T 41 30 1.156 (0.6918–1.931) 0.5801
A 201 170
rs11550470 Additive T/T 1 0 1.499 (0.713–3.151) 0.2857
C/T 19 12
C/C 101 88
Codominant T/T 1 0 NA (NA–NA) NA
C/T 19 12 NA (NA–NA) NA
C/C 101 88
Dominant T/T,C/T 20 12 1.452 (0.6719–3.138) 0.3427
C/C 101 88
Recessive T/T 1 0 NA (NA–NA) NA
C/C,C/T 120 100
Allele T 21 12 1.489 (0.7135–3.106) 0.289
C 221 188
rs11607 Additive T/T 17 23 0.7049 (0.4887–1.017) 0.06143
C/T 50 42
C/C 54 35
Codominant T/T 17 23 0.4791 (0.2246–1.022) 0.05691
C/T 50 42 0.7716 (0.4273–1.393) 0.3898
C/C 54 35
Dominant T/T,C/T 67 65 0.6681 (0.3873–1.153) 0.1471
C/C 54 35
Recessive T/T 17 23 0.5472(0.2737–1.094) 0.08804
C/C,C/T 104 77
Allele T 84 88 0.6766 (0.4606–0.9941) 0.04658
C 158 112
rs12933523 Additive A/A 2 1 1.875(0.8935–3.934) 0.09646
G/A 19 8
G/G 100 91
Codominant A/A 2 1 1.82 (0.1623–20.41) 0.6273
G/A 19 8 2.161 (0.9023–5.177) 0.08376
G/G 100 91
Dominant A/A,G/A 21 9 2.123 (0.9251–4.874) 0.0757
G/G 100 91
Recessive A/A 2 1 1.664 (0.1487–18.62) 0.6795
G/G,G/A 119 99
Allele A 23 10 1.995(0.9263–4.299) 0.07766
G 219 190
rs2280026 Additive C/C 14 7 1.044 (0.6981–1.56) 0.8355
T/C 42 42
T/T 65 51
Codominant C/C 14 7 1.569 (0.5898–4.175) 0.3668
T/C 42 42 0.7846 (0.4467–1.378) 0.3987
T/T 65 51
Dominant C/C,T/C 56 49 0.8967 (0.5275–1.524) 0.6871
T/T 65 51
Recessive C/C 14 7 1.738 (0.673–4.49) 0.2534
T/T,T/C 107 93
Allele C 70 56 1.047 (0.6908–1.585) 0.8301
T 172 144
rs3743631 Additive G/G 16 4 1.638 (1.069–2.509) 0.02341
A/G 55 44
A/A 50 52
Codominant G/G 16 4 4.16 (1.301–13.3) 0.01623
A/G 55 44 1.3 (0.7464–2.264) 0.354
A/A 50 52
Dominant G/G,A/G 71 48 1.538(0.9021–2.623) 0.1137
A/A 50 52
Recessive G/G 16 4 3.657 (1.181–11.32) 0.02452
A/A,A/G 105 96
Allele G 87 52 1.598 (1.059–2.409) 0.02542
A 155 148
rs907045 Additive A/A 4 1 1.831 (1.055–3.177) 0.03147
T/A 38 21
T/T 79 78
Codominant A/A 4 1 3.949 (0.4317–36.13) 0.2239
T/A 38 21 1.787 (0.963–3.314) 0.06569
T/T 79 78
Dominant A/A,T/A 42 22 1.885 (1.031–3.446) 0.03945
T/T 79 78
Recessive A/A 4 1 3.385 (0.3722–30.78) 0.279
T/T,T/A 117 99
Allele A 46 23 1.806(1.052–3.1) 0.03196
T 196 177
rs9922601 Additive A/A 6 6 1.099 (0.6956–1.738) 0.685
T/A 33 22
T/T 82 72
Codominant A/A 6 6 0.878 (0.2712–2.843) 0.8283
T/A 33 22 1.317 (0.7046–2.462) 0.3881
T/T 82 72
Dominant A/A,T/A 39 28 1.223 (0.6851–2.183) 0.496
T/T 82 72
Recessive A/A 6 6 0.8174 (0.2552–2.618) 0.7342
T/T,T/A 115 94
Allele A 45 34 1.115 (0.6826–1.822) 0.6632
T 197 166
  1. SNP single nucleotide polymorphisms, OR odds ratio, CI confidence interval