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Table 3 Genotype distribution and allele frequency of the tested SNPs in patients and controls

From: RETRACTED ARTICLE: Serum sphingosine-1-phosphate levels and Sphingosine-1-Phosphate gene polymorphisms in acute respiratory distress syndrome: a multicenter prospective study

SNP

Model

Genotype

Case

Control

OR (95% CI)

P value

rs1049884

Additive

T/T

2

1

1.173 (0.684–2.009)

0.5619

A/T

37

28

A/A

82

71

Codominant

T/T

2

1

1.732 (0.1538–19.5)

0.6567

A/T

37

28

1.144 (0.6376–2.053)

0.6517

A/A

82

71

–

–

Dominant

T/T,A/T

39

29

1.164 (0.6545–2.072)

0.6045

A/A

82

71

Recessive

T/T

2

1

1.664 (0.1487–18.62)

0.6795

A/A,A/T

119

99

Allele

T

41

30

1.156 (0.6918–1.931)

0.5801

A

201

170

rs11550470

Additive

T/T

1

0

1.499 (0.713–3.151)

0.2857

C/T

19

12

C/C

101

88

Codominant

T/T

1

0

NA (NA–NA)

NA

C/T

19

12

NA (NA–NA)

NA

C/C

101

88

–

–

Dominant

T/T,C/T

20

12

1.452 (0.6719–3.138)

0.3427

C/C

101

88

Recessive

T/T

1

0

NA (NA–NA)

NA

C/C,C/T

120

100

Allele

T

21

12

1.489 (0.7135–3.106)

0.289

C

221

188

rs11607

Additive

T/T

17

23

0.7049 (0.4887–1.017)

0.06143

C/T

50

42

C/C

54

35

Codominant

T/T

17

23

0.4791 (0.2246–1.022)

0.05691

C/T

50

42

0.7716 (0.4273–1.393)

0.3898

C/C

54

35

–

–

Dominant

T/T,C/T

67

65

0.6681 (0.3873–1.153)

0.1471

C/C

54

35

Recessive

T/T

17

23

0.5472(0.2737–1.094)

0.08804

C/C,C/T

104

77

Allele

T

84

88

0.6766 (0.4606–0.9941)

0.04658

C

158

112

rs12933523

Additive

A/A

2

1

1.875(0.8935–3.934)

0.09646

G/A

19

8

G/G

100

91

Codominant

A/A

2

1

1.82 (0.1623–20.41)

0.6273

G/A

19

8

2.161 (0.9023–5.177)

0.08376

G/G

100

91

–

–

Dominant

A/A,G/A

21

9

2.123 (0.9251–4.874)

0.0757

G/G

100

91

Recessive

A/A

2

1

1.664 (0.1487–18.62)

0.6795

G/G,G/A

119

99

Allele

A

23

10

1.995(0.9263–4.299)

0.07766

G

219

190

rs2280026

Additive

C/C

14

7

1.044 (0.6981–1.56)

0.8355

T/C

42

42

T/T

65

51

Codominant

C/C

14

7

1.569 (0.5898–4.175)

0.3668

T/C

42

42

0.7846 (0.4467–1.378)

0.3987

T/T

65

51

–

–

Dominant

C/C,T/C

56

49

0.8967 (0.5275–1.524)

0.6871

T/T

65

51

Recessive

C/C

14

7

1.738 (0.673–4.49)

0.2534

T/T,T/C

107

93

Allele

C

70

56

1.047 (0.6908–1.585)

0.8301

T

172

144

rs3743631

Additive

G/G

16

4

1.638 (1.069–2.509)

0.02341

A/G

55

44

A/A

50

52

Codominant

G/G

16

4

4.16 (1.301–13.3)

0.01623

A/G

55

44

1.3 (0.7464–2.264)

0.354

A/A

50

52

–

–

Dominant

G/G,A/G

71

48

1.538(0.9021–2.623)

0.1137

A/A

50

52

Recessive

G/G

16

4

3.657 (1.181–11.32)

0.02452

A/A,A/G

105

96

Allele

G

87

52

1.598 (1.059–2.409)

0.02542

A

155

148

rs907045

Additive

A/A

4

1

1.831 (1.055–3.177)

0.03147

T/A

38

21

T/T

79

78

Codominant

A/A

4

1

3.949 (0.4317–36.13)

0.2239

T/A

38

21

1.787 (0.963–3.314)

0.06569

T/T

79

78

–

–

Dominant

A/A,T/A

42

22

1.885 (1.031–3.446)

0.03945

T/T

79

78

Recessive

A/A

4

1

3.385 (0.3722–30.78)

0.279

T/T,T/A

117

99

Allele

A

46

23

1.806(1.052–3.1)

0.03196

T

196

177

rs9922601

Additive

A/A

6

6

1.099 (0.6956–1.738)

0.685

T/A

33

22

T/T

82

72

Codominant

A/A

6

6

0.878 (0.2712–2.843)

0.8283

T/A

33

22

1.317 (0.7046–2.462)

0.3881

T/T

82

72

–

–

Dominant

A/A,T/A

39

28

1.223 (0.6851–2.183)

0.496

T/T

82

72

Recessive

A/A

6

6

0.8174 (0.2552–2.618)

0.7342

T/T,T/A

115

94

Allele

A

45

34

1.115 (0.6826–1.822)

0.6632

T

197

166

  1. SNP single nucleotide polymorphisms, OR odds ratio, CI confidence interval
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Journal of Translational Medicine

ISSN: 1479-5876

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