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Table 3 Genotype distribution and allele frequency of the tested SNPs in patients and controls

From: Serum sphingosine-1-phosphate levels and Sphingosine-1-Phosphate gene polymorphisms in acute respiratory distress syndrome: a multicenter prospective study

SNPModelGenotypeCaseControlOR (95% CI)P value
rs1049884AdditiveT/T211.173 (0.684–2.009)0.5619
A/T3728
A/A8271
CodominantT/T211.732 (0.1538–19.5)0.6567
A/T37281.144 (0.6376–2.053)0.6517
A/A8271
DominantT/T,A/T39291.164 (0.6545–2.072)0.6045
A/A8271
RecessiveT/T211.664 (0.1487–18.62)0.6795
A/A,A/T11999
AlleleT41301.156 (0.6918–1.931)0.5801
A201170
rs11550470AdditiveT/T101.499 (0.713–3.151)0.2857
C/T1912
C/C10188
CodominantT/T10NA (NA–NA)NA
C/T1912NA (NA–NA)NA
C/C10188
DominantT/T,C/T20121.452 (0.6719–3.138)0.3427
C/C10188
RecessiveT/T10NA (NA–NA)NA
C/C,C/T120100
AlleleT21121.489 (0.7135–3.106)0.289
C221188
rs11607AdditiveT/T17230.7049 (0.4887–1.017)0.06143
C/T5042
C/C5435
CodominantT/T17230.4791 (0.2246–1.022)0.05691
C/T50420.7716 (0.4273–1.393)0.3898
C/C5435
DominantT/T,C/T67650.6681 (0.3873–1.153)0.1471
C/C5435
RecessiveT/T17230.5472(0.2737–1.094)0.08804
C/C,C/T10477
AlleleT84880.6766 (0.4606–0.9941)0.04658
C158112
rs12933523AdditiveA/A211.875(0.8935–3.934)0.09646
G/A198
G/G10091
CodominantA/A211.82 (0.1623–20.41)0.6273
G/A1982.161 (0.9023–5.177)0.08376
G/G10091
DominantA/A,G/A2192.123 (0.9251–4.874)0.0757
G/G10091
RecessiveA/A211.664 (0.1487–18.62)0.6795
G/G,G/A11999
AlleleA23101.995(0.9263–4.299)0.07766
G219190
rs2280026AdditiveC/C1471.044 (0.6981–1.56)0.8355
T/C4242
T/T6551
CodominantC/C1471.569 (0.5898–4.175)0.3668
T/C42420.7846 (0.4467–1.378)0.3987
T/T6551
DominantC/C,T/C56490.8967 (0.5275–1.524)0.6871
T/T6551
RecessiveC/C1471.738 (0.673–4.49)0.2534
T/T,T/C10793
AlleleC70561.047 (0.6908–1.585)0.8301
T172144
rs3743631AdditiveG/G1641.638 (1.069–2.509)0.02341
A/G5544
A/A5052
CodominantG/G1644.16 (1.301–13.3)0.01623
A/G55441.3 (0.7464–2.264)0.354
A/A5052
DominantG/G,A/G71481.538(0.9021–2.623)0.1137
A/A5052
RecessiveG/G1643.657 (1.181–11.32)0.02452
A/A,A/G10596
AlleleG87521.598 (1.059–2.409)0.02542
A155148
rs907045AdditiveA/A411.831 (1.055–3.177)0.03147
T/A3821
T/T7978
CodominantA/A413.949 (0.4317–36.13)0.2239
T/A38211.787 (0.963–3.314)0.06569
T/T7978
DominantA/A,T/A42221.885 (1.031–3.446)0.03945
T/T7978
RecessiveA/A413.385 (0.3722–30.78)0.279
T/T,T/A11799
AlleleA46231.806(1.052–3.1)0.03196
T196177
rs9922601AdditiveA/A661.099 (0.6956–1.738)0.685
T/A3322
T/T8272
CodominantA/A660.878 (0.2712–2.843)0.8283
T/A33221.317 (0.7046–2.462)0.3881
T/T8272
DominantA/A,T/A39281.223 (0.6851–2.183)0.496
T/T8272
RecessiveA/A660.8174 (0.2552–2.618)0.7342
T/T,T/A11594
AlleleA45341.115 (0.6826–1.822)0.6632
T197166
  1. SNP single nucleotide polymorphisms, OR odds ratio, CI confidence interval