Table 2 20 most differentially expressed proteins in Jurkat and SUDHL5 after SAHA treatment
Gene symbol | Protein name | Fold change* |
|---|---|---|
Jurkat up | ||
RWDD2B | RWD domain-containing protein 2B | 11.3 |
APOB | Apolipoprotein B-100 | 9.8 |
APOC3 | Apolipoprotein C-III | 6.9 |
RETSAT | All-trans-retinol 13,14-reductase | 3.3 |
FERMT2 | Fermitin family homolog 2 | 2.8 |
TUBB2A | Tubulin beta-2A chain | 2.6 |
MT-CO1 | Cytochrome c oxidase subunit 1 | 2.5 |
TUBB3 | Tubulin beta-3 chain | 2.3 |
BAG3 | BAG family molecular chaperone regulator 3 | 2.2 |
H1FX | Histone H1x | 2.1 |
Jurkat down | ||
UNG | Uracil-DNA glycosylase | − 3.3 |
TTC4 | Tetratricopeptide repeat protein 4 | − 2.6 |
TIMM8B | Mitochondrial import inner membrane translocase subunit Tim8 B | − 2.5 |
NAF1 | H/ACA ribonucleoprotein complex non-core subunit NAF1 | − 2.1 |
ZFAND5 | AN1-type zinc finger protein 5 | − 2.0 |
CD3E | T-cell surface glycoprotein CD3 epsilon chain | − 1.9 |
CD247 | T-cell surface glycoprotein CD3 zeta chain | − 1.9 |
TIMM13 | Mitochondrial import inner membrane translocase subunit Tim13 | − 1.9 |
CCDC86 | Coiled-coil domain-containing protein 86 | − 1.9 |
CD3D | T-cell surface glycoprotein CD3 delta chain | − 1.9 |
SUDHL5 up | ||
PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase cat. subunit beta | 8.2 |
PDCD4 | Programmed cell death protein 4 | 4.5 |
MGST3 | Microsomal glutathione S-transferase 3 | 3.4 |
VCL | Vinculin | 3.1 |
HSDL2 | Hydroxysteroid dehydrogenase-like protein 2 | 2.5 |
PNKD | Probable hydrolase PNKD | 2.3 |
ZNF593 | Zinc finger protein 593 | 2.1 |
ACO1 | Cytoplasmic aconitate hydratase | 2.0 |
H1FX | Histone H1x | 2.0 |
ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 2.0 |
SUDHL5 down | ||
TYMS | Thymidylate synthase | − 2.9 |
UBE2C | Ubiquitin-conjugating enzyme E2 C | − 2.7 |
RRM1 | Ribonucleoside-diphosphate reductase large subunit | − 2.6 |
RRM2 | Ribonucleoside-diphosphate reductase subunit M2 | − 2.2 |
SYF2 | Pre-mRNA-splicing factor SYF2 | − 2.1 |
CKS2 | Cyclin-dependent kinases regulatory subunit 2 | − 2.1 |
LARP4 | La-related protein 4 | − 2.1 |
LIMD2 | LIM domain-containing protein 2 | − 2.0 |
MPV17L2 | Mpv17-like protein 2 | − 2.0 |
RSL24D1 | Probable ribosome biogenesis protein RLP24 | − 2.0 |