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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: HDACi mediate UNG2 depletion, dysregulated genomic uracil and altered expression of oncoproteins and tumor suppressors in B- and T-cell lines

Fig. 2

HDAC inhibition mediates downregulation of proteins involved in genomic uracil homeostasis. Enzymes involved in regulation of the cellular dUTP/dTTP ratio as well as processing of genomic uracil are shown, together with their differential expression levels in Jurkat (left bar codes) and SUDHL5 (right bar codes) after SAHA treatment (*; t-test p ≤ 0.05)

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