TY - JOUR AU - Zhang, Yue AU - Ding, Xiaosong AU - Hua, Bing AU - Liu, Qingbo AU - Chen, Hui AU - Zhao, Xue-Qiao AU - Li, Weiping AU - Li, Hongwei PY - 2020 DA - 2020/04/01 TI - Real-world use of ACEI/ARB in diabetic hypertensive patients before the initial diagnosis of obstructive coronary artery disease: patient characteristics and long-term follow-up outcome JO - Journal of Translational Medicine SP - 150 VL - 18 IS - 1 AB - Current guidelines recommend angiotensin-converting-enzyme inhibitors (ACEI)/angiotensin receptor blockers (ARB) as a first-line therapy in diabetic hypertensive patients and for secondary prevention in patients with obstructive coronary artery disease (OCAD). However, the effects of using ACEI/ARB before the initial diagnosis of OCAD on major adverse cardiac and cerebral event (MACCE) in diabetic hypertensive patients remain unclear. This study investigated whether using ACEI/ARB before the initial diagnosis of OCAD could be associated with improved clinical outcomes in diabetic hypertensive patients. SN - 1479-5876 UR - https://doi.org/10.1186/s12967-020-02314-y DO - 10.1186/s12967-020-02314-y ID - Zhang2020 ER -