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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: An integrated prognosis model of pharmacogenomic gene signature and clinical information for diffuse large B-cell lymphoma patients following CHOP-like chemotherapy

Fig. 2

Performance evaluation of the integrated model for OS of DLBCL patients treated with CHOP-based chemotherapy in the validating dataset. Patients’ overall survival status and risk score generated with integrated model in the validating dataset (GSE10846, n = 342). a The distribution plot, patients’ overall survival status and time and heatmap of the integrated model profiles. Rows represent clinical information and drug resistance probability, and columns represent patients. The grey dotted line represents the median integrated model risk score cutoff dividing patients into low- and high-score groups. b The Kaplan–Meier curves for patients in the validating dataset. The two-sided Log-rank test was performed to test the difference for OS between the high-risk and low-risk groups determined based on the median risk score from the validating set patients. The number of patients at risk was listed below the survival curves. The tick marks on the Kaplan–Meier curves represents the censored subjects. c The ROC curve had an AUC of 0.67

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