Fig. 2

LTBP1 was up-regulated in ESCC and associated with lymphatic metastasis. a IHC staining of LTBP1 protein in ESCC and adjacent normal esophageal tissues. LTBP1 was localized in cytoplasm of cancer cells, but rarely expressed in normal esophageal tissues. b Frequency of negative, positive LTBP1 expression in ESCC and adjacent normal esophageal tissue. c Frequency of low/high LTBP1 expression in ESCC when categorized by lymphatic metastasis (Chi Square, *p < 0.05)