Fig. 5

miR-328-3p inhibitor suppresses pHBV1.3-induced HBV activity. THLE-2 cells were co-transfected with pHBV1.3 or empty pcDNA3.1 vector (control), and miR-328-3p inhibitor or inhibitor negative control (NC). a HBV RNA and b HBV DNA were qualified. c, d The OD 450 absorbance values were obtained by ELISA for determining levels of HBsAg and HBeAg in THLE-2 cell supernatants. Values are presented as the mean ± SD (n = 3). ^##P < 0.01 vs. Vector + inhibitor NC. ^&&P < 0.01 vs. inhibitor NC + pHBV1.3