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Table 2 Univariate log-rank analysis and multivariate survival analysis conducted on D2

From: Glandular orientation and shape determined by computational pathology could identify aggressive tumor for early colon carcinoma: a triple-center study

VariablesUnivariate analysisMultivariate analysis
HR (95% CI)PHR (95% CI)P
Gender: male vs. female0.86 (0.52–1.41)0.550  
Age, years: ≥ 65 vs. < 650.81 (0.37–1.76)0.595  
Race: Asia vs. other0.67 (0.04–9.15)0.765  
Histology grade: poorly vs. W/M*1.51 (1.04–2.19)0.0290.21 (0.21–3.81)0.293
Tumor size: ≥ 5 cm vs. < 5 cm0.52 (0.06–4.79)0.564  
Tumor grade: T3/T4 vs. T1/T21.29 (1.01–1.65)0.0340.13 (0.01–1.64)0.115
Perineural invasion: yes vs. no2.37 (1.12–4.98)0.0234.65 (0.51–41.98)0.171
Vascular invasion: yes vs. no2.46 (1.15–5.21)0.0194.83 (0.72–32.60)0.106
MSI status: MSS-H vs. MSS/MSS-L1.08 (1.15–5.21)0.0370.35 (0.08–1.40)0.183
Location: right vs. left0.79 (0.11–2.27)0.362  
Manual grade: high vs. low1.15 (1.01–1.31)0.0360.16 (0.01–1.89)0.146
ECAHBC: positive vs. negative5.63 (1.64–19.31)0.0069.65 (2.15–43.12)0.003
  1. W/M* well/moderately, CI confidence interval, HR hazard ratio, MSI: MSI-L/H microsatellite instability—low/high, MSS microsatellite stable
  2. Values in italic are statistically significant, P < 0.05