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Table 2 Univariate log-rank analysis and multivariate survival analysis conducted on D2

From: Glandular orientation and shape determined by computational pathology could identify aggressive tumor for early colon carcinoma: a triple-center study

Variables Univariate analysis Multivariate analysis
HR (95% CI) P HR (95% CI) P
Gender: male vs. female 0.86 (0.52–1.41) 0.550   
Age, years: ≥ 65 vs. < 65 0.81 (0.37–1.76) 0.595   
Race: Asia vs. other 0.67 (0.04–9.15) 0.765   
Histology grade: poorly vs. W/M* 1.51 (1.04–2.19) 0.029 0.21 (0.21–3.81) 0.293
Tumor size: ≥ 5 cm vs. < 5 cm 0.52 (0.06–4.79) 0.564   
Tumor grade: T3/T4 vs. T1/T2 1.29 (1.01–1.65) 0.034 0.13 (0.01–1.64) 0.115
Perineural invasion: yes vs. no 2.37 (1.12–4.98) 0.023 4.65 (0.51–41.98) 0.171
Vascular invasion: yes vs. no 2.46 (1.15–5.21) 0.019 4.83 (0.72–32.60) 0.106
MSI status: MSS-H vs. MSS/MSS-L 1.08 (1.15–5.21) 0.037 0.35 (0.08–1.40) 0.183
Location: right vs. left 0.79 (0.11–2.27) 0.362   
Manual grade: high vs. low 1.15 (1.01–1.31) 0.036 0.16 (0.01–1.89) 0.146
ECAHBC: positive vs. negative 5.63 (1.64–19.31) 0.006 9.65 (2.15–43.12) 0.003
  1. W/M* well/moderately, CI confidence interval, HR hazard ratio, MSI: MSI-L/H microsatellite instability—low/high, MSS microsatellite stable
  2. Values in italic are statistically significant, P < 0.05