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Table 2 Univariate log-rank analysis and multivariate survival analysis conducted on D2

From: Glandular orientation and shape determined by computational pathology could identify aggressive tumor for early colon carcinoma: a triple-center study

Variables

Univariate analysis

Multivariate analysis

HR (95% CI)

P

HR (95% CI)

P

Gender: male vs. female

0.86 (0.52–1.41)

0.550

  

Age, years: ≥ 65 vs. < 65

0.81 (0.37–1.76)

0.595

  

Race: Asia vs. other

0.67 (0.04–9.15)

0.765

  

Histology grade: poorly vs. W/M*

1.51 (1.04–2.19)

0.029

0.21 (0.21–3.81)

0.293

Tumor size: ≥ 5 cm vs. < 5 cm

0.52 (0.06–4.79)

0.564

  

Tumor grade: T3/T4 vs. T1/T2

1.29 (1.01–1.65)

0.034

0.13 (0.01–1.64)

0.115

Perineural invasion: yes vs. no

2.37 (1.12–4.98)

0.023

4.65 (0.51–41.98)

0.171

Vascular invasion: yes vs. no

2.46 (1.15–5.21)

0.019

4.83 (0.72–32.60)

0.106

MSI status: MSS-H vs. MSS/MSS-L

1.08 (1.15–5.21)

0.037

0.35 (0.08–1.40)

0.183

Location: right vs. left

0.79 (0.11–2.27)

0.362

  

Manual grade: high vs. low

1.15 (1.01–1.31)

0.036

0.16 (0.01–1.89)

0.146

ECAHBC: positive vs. negative

5.63 (1.64–19.31)

0.006

9.65 (2.15–43.12)

0.003

  1. W/M* well/moderately, CI confidence interval, HR hazard ratio, MSI: MSI-L/H microsatellite instability—low/high, MSS microsatellite stable
  2. Values in italic are statistically significant, P < 0.05