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Table 1 Summary of patients’ clinicopathological characteristics

From: Glandular orientation and shape determined by computational pathology could identify aggressive tumor for early colon carcinoma: a triple-center study

VariablesSub variablesTotalD1D2/D3D4
Number of patients 532 (100%)263 (49.4%)223 (41.9%)46 (8.6%)
GenderMale335 (63.0%)162 (61.6%)141 (63.2%)32 (69.6%)
Female197 (37.0%)101 (38.4%)82 (36.8%)14 (30.4%)
Age, years<65141 (29.1%)77 (29.3%)45 (20.2%)19 (41.3%)
≥65391 (70.9%)186 (70.7%)178 (79.8%)27 (58.7%)
RaceAsian523 (96.4%)257 (97.7%)220 (98.7%)46 (100%)
Others9 (3.6%)6 (2.3%)3 (1.3%)0 (0.0%)
Histology gradeW/M**407 (76.5%)198 (75.3%)172 (77.1%)37 (80.4%)
Poorly125 (23.5%)65 (24.7%)51 (22.9%)9 (19.6%)
Tumor size<5 cm397 (75.4%)195 (69.5%)169 (75.8%)33 (71.7%)
≥5 cm135 (24.6%)68 (30.5%)54 (24.2%)13 (28.3%)
Tumor stageT1/T2393 (73.9%)190 (72.2%)166 (74.4%)37 (80.4%)
T3/T4139 (26.1%)73 (27.8%)57 (25.6%)9 (19.6%)
Manual gradelow282 (69.2%)181 (68.8%)156 (70.0%)31 (67.4%)
high164 (30.8%)82 (31.2%)67 (30.0%)15 (32.6%)
LocationRight278 (52.3%)134 (50.9%)117 (52.5%)27 (58.7%)
Left254 (47.7%)129 (49.1%)106 (47.5%)19 (41.3%)
MSI statusMSS/MSS-L451 (84.8%)219 (83.3%)194 (87.0%)38 (82.6%)
MSI-H81 (15.2%)44 (16.7%)29 (13.0%)8 (17.4%)
Perineural invasionYes75 (14.1%)36 (13.7%)33 (14.8%)6 (13.0%)
No457 (85.9%)227 (86.3%)190 (85.2%)40 (87.0%)
Vascular invasionYes68 (12.8%)33 (12.5%)30 (13.5%)5 (10.9%)
No464 (87.2%)230 (87.5%)193 (86.5%)41 (89.1%)
RecurrenceYes112 (21.1%)58 (22.1%)53 (23.8%)6 (13.0%)
No420 (78.9%)205 (77.9%)170 (76.2%)40 (87.0%)
  1. W/M** well/moderately, MSI: MSI-L/H microsatellite instability—low/high, MSS microsatellite stable