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Table 3 Subgroup analyses for the association between SUA trajectories and NAFLD risk

From: Changing trajectories of serum uric acid and risk of non-alcoholic fatty liver disease: a prospective cohort study

  Trajectory 1 Trajectory 2 Trajectory 3 Trajectory 4 Ptrend Pinteraction
Age<60 years 1.00 1.38 (0.95–2.00) 2.03 (1.31–3.15) ** 2.70 (1.50–4.86)** 0.0002 0.4054
Age≥60 years 1.00 0.83 (0.35–1.94) 1.21 (0.52–2.85) 1.24 (0.45–3.42) 0.2167
Male 1.00 0.90 (0.46–1.75) 1.22 (0.64–2.33) 1.53 (0.75–3.13) 0.0135 0.2952
Female 1.00 1.31 (0.87–1.96) 2.94 (1.61–5.38) ** 5.59 (0.25–7.40) 0.0018
Non- obesity 1.00 1.25 (0.80–1.95) 1.67 (1.01–2.76) * 1.96 (1.02–3.78)* 0.0175 0.6230
Abdominal obesity 1.00 1.33 (0.79–2.24) 2.21 (1.23–3.97) ** 2.94 (1.36–6.33)** 0.0010
  1. All analyses were adjusted for age, sex, drinking, smoking, dietary habits, exercise, BMI, abdominal obesity, VAI, BUN, SCr, dyslipidemia, MS, diabetes, hypertension, use of antidyslipidemia medication, and eGFR, except for subgroup variables. Date are shown as OR with 95%CI
  2. SUA serum uric acid, NAFLD non-alcoholic fatty liver disease, OR odds ratio, CI confidence interval, BMI body mass index, VAI visceral fat index, BUN blood urea nitrogen, SCr serum creatinine, eGFR estimated glomerular filtration rate, MS metabolic syndrome
  3. *P < 0.05, **P < 0.01