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Table 2 Association between SUA trajectories and NAFLD risk during follow-up

From: Changing trajectories of serum uric acid and risk of non-alcoholic fatty liver disease: a prospective cohort study

Models Trajectory 1 Trajectory 2 Trajectory 3 Trajectory 4 Ptrend
Model 1 1.00 1.64 (1.28–2.20)* 3.16 (2.38–4.20)** 4.32 (2.96–6.29)** < 0.001
Model 2 1.00 1.54 (1.12–2.12)* 2.78 (1.96–3.94)** 3.79 (2.44–5.88)** < 0.001
Model 3 1.00 1.27 (0.91–1.78) 1.89 (1.29–2.75)** 2.34 (1.43–3.83)** < 0.001
  1. Model 1: unadjusted baseline variables. And the C statistic was 0.63 (95% CI 0.6–0.66)
  2. Model 2: adjusted for age and sex. And the C statistic was 0.64 (95% CI 0.61–0.66)
  3. Model 3: adjusted for age, sex, drinking, smoking, dietary habits, exercise, BMI, abdominal obesity, VAI, BUN, SCr, eGFR, dyslipidemia, MS, diabetes, hypertension, and use of antidyslipidemia medication. And the C statistic was 0.76 (95% CI 0.73–0.77)
  4. All data are expressed as OR with 95%CI
  5. SUA serum uric acid, NAFLD non-alcoholic fatty liver disease, OR odds ratio, CI confidence interval, BMI body mass index, VAI visceral fat index, BUN blood urea nitrogen, SCr serum creatinine, eGFR estimated glomerular filtration rate, MS metabolic syndrome
  6. *P < 0.050, **P < 0.010