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Table 3 Cox models

From: Patients with stage IV epithelial ovarian cancer: understanding the determinants of survival

VariablesUnivariable analysisMultivariable analysis
HR (95% CI)p-valueHR (95% CI)p-value
Age > 65 years2.4 (1.6–3.6)< 0.001  
Surgical complexity 0.104
 LowRef   
 Intermediate1.2 (0.7–2.3)   
 High0.5 (0.3–1.0)   
CA 125 > 5001.0 (0.6–1.6)0.96
Chemotherapy onlyRef< 0.001  
 NACT– IDS0.2 (0.1–0.3) 0.48 (0.22–1.01)0.054
 PDS0.1 (0.1–0.2) 0.32 (0.14–0.71)0.005
Postoperative residual disease > 0Ref< 0.001  
 Postoperative residual disease = 0 (complete surgery)0.2 (0.20–0.21) 0.37 (0.18–0.75)0.006
Association of Carboplatin and Paclitaxel0.4 (0.2–0.56)< 0.0010.45 (0.25–0.80)0.007
Metastatic locations
 Hepatic1.3 (0.8–2.1)0.213
 Pleural effusion1.5 (1.0–2.3)0.0658
 Solid pleural lesion1.2 (0.6–2.6)0.576
 Supra-diaphragmatic lesion1.1 (0.7–1.8)0.693
 Deep intra—abdominal organ0.5 (0.2–0.95)0.0209  
  1. Univariable and multivariable analysis of the factors influencing overall survival in patients with stage IV epithelial ovarian cancer