Table 1 Main characteristics of the patients included
From: Patients with stage IV epithelial ovarian cancer: understanding the determinants of survival
Chemotherapy only N = 65 | Primary debulking Surgery N = 52 | Interval debulking surgery N = 91 | p-value | |
|---|---|---|---|---|
Age (years) | 68.4 (57–78) | 56.6 (47.8–67.25) | 58.8 (51–66.5) | < 0.001 |
BMI | 25.0 (21.0–27.5) | 26.7 (22.1–29.7) | 24.6 (20.4–26.4) | 0.16 |
Histology | ||||
Serous | 57 (87.7) | 30 (57.7) | 73 (80.2) | < 0.001 |
Mucinous | 1 (1.5) | 2 (3.8) | 1 (1.1) | |
Endometrioid | 0 | 4 (7.7) | 9 (9.9) | |
Transitional cell | 0 | 1 (1.9) | 0 | |
Clear cell | 1 (1.5) | 4 (7.7) | 0 | |
Mixed | 0 | 6 (11.5) | 5 (5.5) | |
Other | 3 (4.6) | 3 (5.8) | 2 (2.2) | |
Unknown | 3 (4.6) | 2 (3.8) | 1 (1.1) | |
Metastasis site | ||||
Intrahepatic | 22 (33.8) | 14 (26.9) | 20 (22.0) | 0.25 |
Intra abdominal organ metastasesa | 11 (16.9) | 16 (30.8) | 15 (16.5) | 0.3 |
Pleural effusion | 23 (35.4) | 9 (17.3) | 41 (45.1) | 0.003 |
Pleural metastasis | 8 (12.3) | 3 (5.8) | 11 (12.1) | 0.42 |
Over diaphragmatic metastases | 16 (24.6) | 12 (23.1) | 24 (26.4) | 0.9 |
Unknown | 16 (24.6) | 0 | 0 | |
CA125 level at diagnosis | 4450 (378–2275) | 1451 (227–1553) | 2499 (530–3193) | 0.04 |
Initial chemotherapy | ||||
Received platinum | 44 (67.7) | 47 (90.4) | 78 (85.7) | 0.002 |
Received taxane | 40 (61.5) | 40 (76.9) | 73 (80.2) | 0.03 |