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Table 2 Univariate Cox’s proportional hazards model assessing factors associated with mortality after diagnosis of mixed adenoneuroendocrine carcinoma in the gastrointestinal tract

From: Gastrointestinal mixed adenoneuroendocrine carcinoma: a population level analysis of epidemiological trends

Risk factorHazard ratios (HR)a95% CIP value
LowerUpper
Age at diagnose (years)
 60Referent   
 > 601.521.171.980.002
Race
 OtherReferent   
 White1.870.963.660.07
 Black2.070.984.370.05
SEER stage
 LocalizedReferent   
 Regional4.962.898.53< 0.001
 Distant16.919.9528.73< 0.001
Treatment
 SurgeryReferent   
 No surgery3.011.974.62< 0.001
Grade
 Well differentiatedReferent   
 Moderately differentiated1.930.933.990.08
 Poorly differentiated4.492.348.65< 0.001
 Undifferentiated3.391.517.620.003
Regional lymph nodes
 NegativeReferent   
 Positive6.534.379.75< 0.001
Tumor size
 2 cmReferent   
 > 2 cm3.622.205.97< 0.001
Tumor site
 AppendixReferent   
 Colon1.811.222.690.003
 Cecum2.111.433.13< 0.001
  1. aHRs greater than 1.0 indicate a higher risk of death