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Table 3 Binary logistic regression analyses for the association of serum HER2 levels with the presence of CAD

From: Association between serum HER2/ErbB2 levels and coronary artery disease: a case–control study

  Model 1 Model 2 Model 3
OR (95% CI) P value OR (95% CI) P value OR (95% CI) P value
Each 1-SD increase 1.323 (1.086–1.612) 0.005 1.533 (1.231–1.908) < 0.001 1.438 (1.130–1.830) 0.003
Quartiles of HER2
Quartile 1 1 1 1
Quartile 2 1.476 (0.863–2.524) 0.155 1.578 (0.892–2.791) 0.117 1.757 (0.960–3.216) 0.068
Quartile 3 0.787 (0.461–1.343) 0.379 0.929 (0.527–1.636) 0.798 0.869 (0.471–1.602) 0.653
Quartile 4 2.104 (1.215–3.644) 0.008 2.866 (1.579–5.202) 0.001 2.365 (1.242–4.503) 0.009
  1. Model 1 was the unadjusted model; Model 2 was adjusted for age and sex; Model 3 was adjusted for age, sex, BMI, smoking habit, hypertension, diabetes, dyslipidemia, and eGFR. CI, confidence interval; HER2, human epidermal growth factor receptor 2; OR, odds ratio; SD, standard deviation