From: Association between serum HER2/ErbB2 levels and coronary artery disease: a case–control study
CAD group (n = 237) | Control group (n = 198) | P value | |
---|---|---|---|
Age (years) | 61 ± 10 | 57 ± 10 | < 0.001 |
Male gender | 176 (74%) | 116 (59%) | 0.001 |
BMI (kg/m2) | 24.48 ± 3.31 | 24.25 ± 3.56 | 0.475 |
Smoking habit | 0.001 | ||
Never smoker | 135 (57%) | 146 (74%) | |
Former smoker | 16 (7%) | 10 (5%) | |
Current smoker | 86 (36%) | 42 (21%) | |
Hypertension | 155 (65%) | 107 (54%) | 0.016 |
Diabetes | 77 (33%) | 27 (14%) | < 0.001 |
Dyslipidemia | 159 (67%) | 116 (59%) | 0.067 |
HbA1c (%) | 6.1 (5.7–6.8) | 5.9 (5.6–6.2) | < 0.001 |
Fasting glucose (mmol/L) | 4.9 (4.5–5.8) | 4.7 (4.3–5.1) | 0.001 |
Total cholesterol (mmol/L) | 4.73 ± 1.17 | 4.60 ± 1.05 | 0.259 |
Triglycerides (mmol/L) | 1.55 (1.04–2.32) | 1.27 (0.85–1.82) | < 0.001 |
LDL-C (mmol/L) | 2.86 ± 1.01 | 2.74 ± 0.87 | 0.180 |
HDL-C (mmol/L) | 0.99 (0.87–1.16) | 1.06 (0.91–1.25) | 0.006 |
Serum creatinine (µ mol/L) | 82 (71–95) | 74 (63–83) | < 0.001 |
eGFR (mL/min/1.73 m2) | 84 (72–95) | 93 (83–99) | < 0.001 |
HER2 (pg/mL) | 4851 ± 1045 | 4596 ± 781 | 0.004 |