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Table 1 Baseline data

From: Association between serum HER2/ErbB2 levels and coronary artery disease: a case–control study

  CAD group (n = 237) Control group (n = 198) P value
Age (years) 61 ± 10 57 ± 10 < 0.001
Male gender 176 (74%) 116 (59%) 0.001
BMI (kg/m2) 24.48 ± 3.31 24.25 ± 3.56 0.475
Smoking habit    0.001
 Never smoker 135 (57%) 146 (74%)  
 Former smoker 16 (7%) 10 (5%)  
 Current smoker 86 (36%) 42 (21%)  
Hypertension 155 (65%) 107 (54%) 0.016
Diabetes 77 (33%) 27 (14%) < 0.001
Dyslipidemia 159 (67%) 116 (59%) 0.067
HbA1c (%) 6.1 (5.7–6.8) 5.9 (5.6–6.2) < 0.001
Fasting glucose (mmol/L) 4.9 (4.5–5.8) 4.7 (4.3–5.1) 0.001
Total cholesterol (mmol/L) 4.73 ± 1.17 4.60 ± 1.05 0.259
Triglycerides (mmol/L) 1.55 (1.04–2.32) 1.27 (0.85–1.82) < 0.001
LDL-C (mmol/L) 2.86 ± 1.01 2.74 ± 0.87 0.180
HDL-C (mmol/L) 0.99 (0.87–1.16) 1.06 (0.91–1.25) 0.006
Serum creatinine (µ mol/L) 82 (71–95) 74 (63–83) < 0.001
eGFR (mL/min/1.73 m2) 84 (72–95) 93 (83–99) < 0.001
HER2 (pg/mL) 4851 ± 1045 4596 ± 781 0.004
  1. Continuous variables are presented as mean ± SD (for normal distributions) or median (interquartile range) (for skewed distributions). Categorical variables are presented as n (%)
  2. BMI body mass index, eGFR estimated glomerular filtration rate, HbA1c hemoglobin A1c, HDL-C high-density lipoprotein cholesterol, HER2 human epidermal growth factor receptor 2, LDL-C low-density lipoprotein cholesterol