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Table 1 Baseline data

From: Association between serum HER2/ErbB2 levels and coronary artery disease: a case–control study

 

CAD group (n = 237)

Control group (n = 198)

P value

Age (years)

61 ± 10

57 ± 10

< 0.001

Male gender

176 (74%)

116 (59%)

0.001

BMI (kg/m2)

24.48 ± 3.31

24.25 ± 3.56

0.475

Smoking habit

  

0.001

 Never smoker

135 (57%)

146 (74%)

 

 Former smoker

16 (7%)

10 (5%)

 

 Current smoker

86 (36%)

42 (21%)

 

Hypertension

155 (65%)

107 (54%)

0.016

Diabetes

77 (33%)

27 (14%)

< 0.001

Dyslipidemia

159 (67%)

116 (59%)

0.067

HbA1c (%)

6.1 (5.7–6.8)

5.9 (5.6–6.2)

< 0.001

Fasting glucose (mmol/L)

4.9 (4.5–5.8)

4.7 (4.3–5.1)

0.001

Total cholesterol (mmol/L)

4.73 ± 1.17

4.60 ± 1.05

0.259

Triglycerides (mmol/L)

1.55 (1.04–2.32)

1.27 (0.85–1.82)

< 0.001

LDL-C (mmol/L)

2.86 ± 1.01

2.74 ± 0.87

0.180

HDL-C (mmol/L)

0.99 (0.87–1.16)

1.06 (0.91–1.25)

0.006

Serum creatinine (µ mol/L)

82 (71–95)

74 (63–83)

< 0.001

eGFR (mL/min/1.73 m2)

84 (72–95)

93 (83–99)

< 0.001

HER2 (pg/mL)

4851 ± 1045

4596 ± 781

0.004

  1. Continuous variables are presented as mean ± SD (for normal distributions) or median (interquartile range) (for skewed distributions). Categorical variables are presented as n (%)
  2. BMI body mass index, eGFR estimated glomerular filtration rate, HbA1c hemoglobin A1c, HDL-C high-density lipoprotein cholesterol, HER2 human epidermal growth factor receptor 2, LDL-C low-density lipoprotein cholesterol