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Table 2 Association between monocyte subsets and TLRS expression and the diagnosis of idiopathic inflammatory myopathies

From: TLR expression in peripheral monocyte subsets of patients with idiopathic inflammatory myopathies: association with clinical and immunological features

Variable Cutoff value Area under the curve (95% CI) Sensitivity (95% CI) Specificity (95% CI) Likelihood ratio (+) P
Mean fluorescence intensity of TLR4 in non-classical monocytes (arbitrary units) > 733.5 0.94 (0.88–1) 88.37 (75.52–94.93) 93.33 (70.18–99.66) 13.26 < 0.0001
Mean fluorescence intensity of TLR4 in intermediate monocytes (arbitrary units) > 2023 0.90 (0.80–1) 54.76 (39.93–68.78) 93.33 (70.18–99.66) 8.21 < 0.0001
Mean fluorescence intensity of TLR4 in classical monocytes (arbitrary units) > 967 0.88 (0.75–1) 90.48 (77.93–96.23) 86.67 (62.12–97.63) 6.78 < 0.0001
% of intermediate monocytes > 20.6 0.83 (0.71–0.95) 36.36 (23.78–51.13) 93.3 (70.18–99.66) 5.45 0.0001