Fig. 2

Anti-P-selectin mAb treatment ameliorated kidney injury in MRL/lpr mice. a Representative PAS staining micrographs of the glomerulus and tubulointerstitium in the C57BL/6, MRL/lpr, saline, and anti-P-selectin groups (magnification of ×400). b Semi-quantitative score of lesions in terms of kidney and tubulointerstitium. **P < 0.01 compared with C57BL/6 group; ^##P < 0.01 compared with saline group. c Urinary albumin-creatinine ratio of the MRL/lpr group compared with the C57BL/6 group at the age of 12 weeks. The results are presented as the medium (first quartile, third quartile). **P < 0.01 between the indicated two groups (n = 10–13 for each group). d Serum anti-dsDNA levels of each group. *P < 0.05 compared with the MRL/lpr, saline, and anti-P-selection groups as analyzed by ANOVA followed by Tukey’s multiple comparisons test. e Complement C3 levels of each group. No statistical significance among groups