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Table 1 Demographic and clinical characteristics of the study population

From: Characteristics of the urinary microbiome in kidney stone patients with hypertension

CharacteristicHC (n = 12)Value for cohort (na)b or statisticp valuec
KSD-NTN (n = 12)KSD-pHTN (n = 11)KSD-HTN (n = 27)
Male [no. (%)]9 (75.00)6 (50.00)4 (36.00)23 (85.10)0.013
Married status [no. (%)]12 (100.00)12 (100.00)11 (100.00)27 (100.00)1.000
Age58.91 ± 18.9747.33 ± 14.9554.09 ± 13.0354.74 ± 12.360.270
Body mass index (kg/m2)25.08 ± 3.3322.67 ± 2.1324.38 ± 1.6925.82 ± 2.800.011
History of drinking0 (0.00)1 (8.33)2 (18.18)1 (3.70)0.291
History of smoking0 (0.00)1 (8.33)1 (9.09)4 (14.81)0.546
Urinary tract infection in previous 1 month0 (0.00)1 (8.33)0 (0.00)0 (0.00)0.340
Duration of stones (years)0.375
 < 0.5 year [no. (%)]NA11 (91.67)10 (90.91)25 (92.59) 
 0.5 to 1 year [no. (%)]NA1 (8.33)1 (9.09)0 (0.00) 
 > 1 year [no. (%)]NA0 (0.00)0 (0.00)2 (7.41) 
Duration of hypertension (years)NANANA4.48 ± 4.59NA
Systolic blood pressure (mmHg)121.83 ± 5.52113.58 ± 8.35131.45 ± 7.46151.11 ± 9.680.000
Diastolic blood pressure (mmHg)74.92 ± 7.7970.33 ± 4.6480.64 ± 7.0692.00 ± 9.740.000
Comorbidities
 Type 2 diabetic mellitus [no. (%)]01 (8.33)4 (36.36)5 (18.52)0.055
 Coronary heart disease [no. (%)]00 (0.00)0 (0.00)2 (7.41)0.332
Serum creatinine (μmol/L)68.90 ± 10.7772.89 ± 21.9073.78 ± 28.8093.56 ± 40.360.069
Blood urea nitrogen (mmol/L)5.75 ± 1.615.75 ± 1.145.06 ± 1.436.20 ± 2.250.387
Estimated glomerular filtration rate (mL/min/1.73 m2)97.45 ± 13.9695.58 ± 20.9589.91 ± 21.8082.89 ± 26.190.209
Urinary pH6.34 ± 0.656.38 ± 0.885.77 ± 0.826.39 ± 1.120.314
  1. HC healthy controls, HTN hypertension, KSD kidney stone disease, NA not applicable, NTN normotension, pHTN pre-hypertension
  2. an, no. of subjects
  3. bMean ± SD or no. (%)
  4. cFisher’s exact test was used for categorical variables and one-way analysis of variance was used to compare continuous variables