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Table 1 Demographic and clinical characteristics of the study population

From: Characteristics of the urinary microbiome in kidney stone patients with hypertension

Characteristic

HC (n = 12)

Value for cohort (na)b or statistic

p valuec

KSD-NTN (n = 12)

KSD-pHTN (n = 11)

KSD-HTN (n = 27)

Male [no. (%)]

9 (75.00)

6 (50.00)

4 (36.00)

23 (85.10)

0.013

Married status [no. (%)]

12 (100.00)

12 (100.00)

11 (100.00)

27 (100.00)

1.000

Age

58.91 ± 18.97

47.33 ± 14.95

54.09 ± 13.03

54.74 ± 12.36

0.270

Body mass index (kg/m2)

25.08 ± 3.33

22.67 ± 2.13

24.38 ± 1.69

25.82 ± 2.80

0.011

History of drinking

0 (0.00)

1 (8.33)

2 (18.18)

1 (3.70)

0.291

History of smoking

0 (0.00)

1 (8.33)

1 (9.09)

4 (14.81)

0.546

Urinary tract infection in previous 1 month

0 (0.00)

1 (8.33)

0 (0.00)

0 (0.00)

0.340

Duration of stones (years)

0.375

 < 0.5 year [no. (%)]

NA

11 (91.67)

10 (90.91)

25 (92.59)

 

 0.5 to 1 year [no. (%)]

NA

1 (8.33)

1 (9.09)

0 (0.00)

 

 > 1 year [no. (%)]

NA

0 (0.00)

0 (0.00)

2 (7.41)

 

Duration of hypertension (years)

NA

NA

NA

4.48 ± 4.59

NA

Systolic blood pressure (mmHg)

121.83 ± 5.52

113.58 ± 8.35

131.45 ± 7.46

151.11 ± 9.68

0.000

Diastolic blood pressure (mmHg)

74.92 ± 7.79

70.33 ± 4.64

80.64 ± 7.06

92.00 ± 9.74

0.000

Comorbidities

 Type 2 diabetic mellitus [no. (%)]

0

1 (8.33)

4 (36.36)

5 (18.52)

0.055

 Coronary heart disease [no. (%)]

0

0 (0.00)

0 (0.00)

2 (7.41)

0.332

Serum creatinine (μmol/L)

68.90 ± 10.77

72.89 ± 21.90

73.78 ± 28.80

93.56 ± 40.36

0.069

Blood urea nitrogen (mmol/L)

5.75 ± 1.61

5.75 ± 1.14

5.06 ± 1.43

6.20 ± 2.25

0.387

Estimated glomerular filtration rate (mL/min/1.73 m2)

97.45 ± 13.96

95.58 ± 20.95

89.91 ± 21.80

82.89 ± 26.19

0.209

Urinary pH

6.34 ± 0.65

6.38 ± 0.88

5.77 ± 0.82

6.39 ± 1.12

0.314

  1. HC healthy controls, HTN hypertension, KSD kidney stone disease, NA not applicable, NTN normotension, pHTN pre-hypertension
  2. an, no. of subjects
  3. bMean ± SD or no. (%)
  4. cFisher’s exact test was used for categorical variables and one-way analysis of variance was used to compare continuous variables